These researchers found that lactose monohydrate had three absorption peaks at 0.53, 1.19 and 1.38 THz, while D-glucose only had one absorption peak at 1.44 THz, suggesting that lactose monohydrate and D-glucose presented different terahertz fingerprint absorption characteristics. A person may experience amplified side effects if they undergo both radiation and chemotherapy. 6. Google Scholar.
Terahertz spectroscopy could distinguish the absorption of different DNA molecules. The unique iTeraCare Terahertz Therapy Device resonates the same frequency as normal human cells, which is 2 to 17 THz, generating MILLIONS of therapeutic entraining vibrations per second into your cells and your body. I had a man by the name of John King who said when I returned he would like to give me a treatment. An increasing interest in the area of biological effects at exposure of tissues and cells to the terahertz (THz) radiation is driven by a rapid progress in THz biophotonics, observed during the past decades. [57] radiated mouse pluripotent stem cells with broadband terahertz waves at 10 THz. 2020;42(23):226773+89. -, Smolyanskaya O., et al. We start with a brief overview of general features of the THz-wave-tissue interactions, as well as modern THz emitters, with an emphasis on those that are reliable for studying the biological effects of THz waves. Cite this article. Terahertz waves are sensitive to the alteration of DNA structures mainly through a collective vibrational mode, which is determined by molecular configuration and spatial conformation. Terahertz is an electromagnetic wave band between microwave and infared. Kang L, Yan Q, Hu YS, Yin HY, Yu SG, Zhou X. Terahertz technology and application of traditional Chinese medicine. If we cut the battery in half, it would not recharge to full again and so our cells are replicating to the level they have gotten down too. Google Scholar. government site. Optical Quartz amplifies the energy generated by the device, creating a more powerful result. Biological effects of in vitro THz radiation exposure in human foetal fibroblasts. Anticancer drugs are pivotal to cancer treatment, but their toxicity may not always be limited to cancer cells, resulting in harmful side-effects. https://doi.org/10.3969/j.issn.1004-9398.2004.04.006. Over night it infected..so drove him to an animal hospital..he spent 10 days there..with tubes..intraveinous liquids..couldnt get up..his heart was working on one ventricule only, his kidneys were shutting down, his spleen was twisted as was his stomach..he was opened up again: spleen removed. Google Scholar. Terahertz radiation exposure results in altered gene expression profile in mouse retina. He was 4yrs old, big mutt about 80lbs. 2 years later, he fell in a roaring river. The MarketWatch News Department was not involved in the creation of this content. We distinguish thermal and nonthermal mechanisms of THz-wave-cell interactions and discuss a problem of adequate estimation of the THz biological effects' specificity. Then, we consider three levels of biological system organization, at which the exposure effects are considered: (i) solutions of biological molecules; (ii) cultures of cells, individual cells, and cell structures; and (iii) entire organs or organisms; special attention is devoted to the cellular level. The team found that the number of infected cells increased more than six times after six hours of exposure. Read more about the first time a study has found there to be side effects from exposure to terahertz radiation. In panel (b), disturbances in the neurites growth zone, and cessation of their further growth, including the disordering in the interneuronic links, are observed. Wu HH. Briefly, terahertz waves altered the space conformation of biomacromolecules by exciting rotational energy levels, which in turn influenced the effects on biomacromolecules and finally resulted in structural and functional changes in organisms. With the rapid development of terahertz technologies, basic research and applications of terahertz waves in biomedicine have attracted increasing attention. Among the causes of eye disease are high blood pressure and reduced blood flow. Inset shows a scheme of the simulated system, where red and gray balls indicate the oxygen and hydrogen atoms, respectively, whereas cyan tube stands for the 1D water channel, and two cyan sheets denote the supporting membrane. Mid-infrared spectroscopy measures the vibration patterns of bending and stretching motions (such as C-O, C=O). Liang PL, Dai JM. However, it could excite the rotational energy level of proteins to alter the spatial conformation and might influence the interactions between proteins. I spent 9 days in the hospital in the hallway with no testing done and was sent home with zero answers. Wang WN, Li YB, Yue WW. Better absorption. https://doi.org/10.3964/j.issn.1000-0593(2009)11-2885-04. Acta Phys Sin. Wilmink GJ, Rivest BD, Roth CC, Ibey BL, Payne JA, Cundin LX, et al. Wang YF, Wei WC, Zhou FJ, Xue ZH. [51] suggested that 1.7 THz high-power terahertz exposure resulted in DNA demethylation in hematological tumor cells. Approach: The problem of experimental data reproducibility, caused by rareness of the THz experimental setups and an absence of unitary protocols, is also considered. The absorption of different sugars in the measured band was significantly different. Twenty four-hour exposure to a 0.12 THz electromagnetic field does not affect the genotoxicity, morphological changes, or expression of heat shock protein in HCE-T cells. Biomed Opt Express. By using this website, you agree to our 1) Fingerprint spectrality. Terms and Conditions, Terahertz radiation accelerated chondrocyte differentiation of MSCs. All bodily functions rely on the availability of nutrients. Borovkova M, Serebriakova M, Fedorov V, Sedykh E, Vaks V, Lichutin A, et al. [44] found terahertz waves downregulated synuclein (SYN) expression in primary hippocampal neurons and downregulated postsynaptic density protein 95 (PSD-95) expression in primary cortical neurons, indicating different cells expressed different proteins by terahertz waves. PubMed Titova LV, Ayesheshim AK, Golubov A, Rodriguez-Juarez R, Woycicki R, Hegmann FA, et al.
[60] used broadband terahertz waves at 10 THz in the center to radiate mouse mesenchymal stem cells (MSCs). Effect of terahertz pulse on gene expression in human eye cells. Permeability changes induced by 130 GHz pulsed radiation on cationic liposomes loaded with carbonic anhydrase. PubMed Central Williams R, Schofield A, Holder G, Downes J, Edgar D, Harrison P, et al. WebLower blood viscosity: Terahertz water has the ability to thin the blood, which can help to lower blood pressure and improve circulation. 2005;12(12):146974. The summarized data demonstrate the current stage of the research activity and knowledge about the THz exposure on living objects. The MarketWatch News Department was not involved in the creation of this content. Homenko et al. , Biomedical applications of terahertz spectroscopy and imaging, Trends Biotechnol. (a)Schematic of the experimental setup. Six hours after radiation, the expression of numerous genes, such as proto-oncogenes and anaplastic lymphoma kinase (ALK), was upregulated. Nanjing: Nanjing Med Univ; 2013. Quantum Electron. Ma X, Zhao HW, Liu GF, Ji T, Zhang ZY, Dai B. Qualitative and quantitative analyses of some saccharides by terahertz time-domain spectroscopy. Lasers Surg Med. Sickness and pain cant exist in full, healthy cells. 2013;58(2):37391. WebThere are no side effects, but there are a few limitations. Cao C. Protein molecules conformation recognition and their interactions characterization based on terahertz spectroscopy. A number of scientific problems and technological barriers need to be addressed, such as the distinct sensitivity of different biomacromolecules to terahertz waves and the roles of terahertz parameters on the effects of biomacromolecules. The terahertz absorption spectra of the five main bases are different from each other, and the same absorption peak represents a shared base. Article They explored whether the expression of phosphorylated histone H2AX (H2AX) was altered after radiation for 2h. In addition to proteins and nucleic acids, other biomacromolecules, such as lipids, are affected by terahertz waves. The UV beam at 270 nm was, Actin polymerization affected by the THz exposure in an aqueous solution. [50] showed that exposure to 1.5 THz FEL at 100 pulses directly reduced absorption in DNA molecules and inhibited DNA synthesis in mammalian cells. The dipole-dipole interactions between C and G and between A and T are the physicochemical basis for DNA replication. Bioelectromagnetics. WebHere are some common side effects to using terahertz devices from iTeraCare that you might experience during use or shortly after: Feeling hot/cold: When a person feels hot Generates Scalar Wave Energy that energizes our cells, balances bodily systems, strengthens the body, produces healing energy and penetrates deeper into the vital organs. Investigation of terahertz radiation influence on rat glial cells. Yanina IY, Nikolaev VV, Zakharova OA, Borisov AV, Dvoretskiy KN, Berezin KV, Kochubey VI, Kistenev YV, Tuchin VV. Coherent measurement of terahertz pulses can directly measure the amplitude and phase and extract the refractive index and absorption parameters to improve the accuracy and reliability [8]. Despite the attractiveness of THz technology for medical diagnosis and therapy, there is still quite limited knowledge about safe limits of THz exposure. https://doi.org/10.1016/j.mrgentox.2015.06.003. Hes much more confident and mellow too. Nikitkina AI, Bikmulina PY, Gafarova ER, Kosheleva NV, Efremov YM, Bezrukov EA, Butnaru DV, Dolganova IN, Chernomyrdin NV, Cherkasova OP, Gavdush AA, Timashev PS. Some molecular rotations, skeleton vibrations of macromolecules, weak intermolecular interaction and crystalline phonon vibrations etc correspond to terahertz bands. 2010;5(12):e15806. [39] found that the levels of tumor suppressor proteins, cell cycle regulatory proteins, and damage repair proteins were upregulated in artificial human skin tissues after exposure to terahertz waves with a strong pulse of (0.11.0) J. However, related studies are lacking. Terahertz waves strongly interact with biomacromolecules, and the terahertz spectrum of biomacromolecules contains numerous physical and chemical information. 2019 Oct;32(10):739-754. doi: 10.3967/bes2019.094. https://doi.org/10.3967/bes2019.094. 2022 Oct 1;12(10):2395. doi: 10.3390/diagnostics12102395. Therefore, terahertz waves are potential and sensitive tools to identify and analyze physical and chemical processes during the synthesis and catabolism of nucleic acids. Follow. [54] discovered that exposure to (0.13.0) THz terahertz wave for 60min, with an average intensity of 60W/cm2, could not damage the integrity of DNA in spermatozoa. Song GA. Effect of terahertz waves on proteins. I left him there, got the car, scrammed it through the forest(thumbs up for old 44 golf) and he managed to scrambled in..drove to vet. Cheon H, Paik JH, Choi M, Yang HJ, Son JH. However, there are still several problems and challenges that need to be solved, some of which are presented as follows. .am letting go..too much blood had been lost I thought. -. 2007;28(8):58798. https://doi.org/10.3724/SP.J.1206.2009.00479. Maybe our cell energy is reduced to 80% then as time and trauma take their toll it goes down to 50% you only have to look at people to see how much they are lacking energy!!! 2021;137(3):58-67. doi: 10.17116/oftalma202113703158. Hintzsche et al. What does terahertz mean? With time, the high pressure can cause severe damage to the optic nerve tissue which in turn can cause blindness. Under certain conditions, linear and nonlinear interactions between the terahertz electromagnetic field and DNA resonance might significantly alter DNA replication and synthesis and even induce local bubbles in the DNA strands [48]. Zhao JW, He MX, Dong LJ, Li SX, Liu LY, Bu SC, et al. https://doi.org/10.3724/SP.J.1187.2012.00471. My head bob-is gone (it never came back) my speech is fine now( that never came back since first night) my bladder and bowel issues gone. Thermal effects of THz exposure are also applicable in cancer treatment, but they are less studied. Homenko A, Kapilevich B, Kornstein R, Firer MA. Ten minutes after exposure, the phosphorylation activity of histone H2AX was increased with the upregulated expression of the apoptosis-related proteins p53 and KU70 and the cell cycle regulatory proteins p21, p16, p15 and p27. [42] discovered that green fluorescent protein expression was induced in Escherichia coli after exposure for 15min under constant terahertz radiation at 1.4W/cm2. [47] also reported that a 5mW/cm2 terahertz wave at 0.12 THz did not influence heat shock protein expression in human corneal epithelial cells (HCE-T). J Lanzhou Univ. Within 2 months of will and TLC, he was back out running . PubMedGoogle Scholar. As we age we notice how much longer it takes and sometimes it just doesnt work at all. Most of the studies suggest that terahertz radiation can only affect biological macromolecules under high power, long-term exposure and at a specific frequency. WebFollowing are the benefits or advantages of Terahertz (THz): It offers greater bandwidth than microwave frequencies. 2019;46(6):16979. Health Phys. Please enable it to take advantage of the complete set of features! https://doi.org/10.1016/j.physleta.2009.12.077. They observed that terahertz waves could lead to abnormal retinal gene expression and tissue damage after 2min of radiation. I was shocked, and elated. https://doi.org/10.1364/BOE.8.000273. Hangzhou: Zhejiang Univ; 2018. The wavelength of terahertz waves is shorter than that of microwaves, which could produce a higher spatial resolution. Xu H, Li WX. Bioelectromagnetics. Infrared bands include far-infrared, Mid-infrared and near-infrared. I was having nerve pain, burning , pins and needles numbness. Courtesy of D.S. (b)A Venn diagram indicating the number of unique and common differently expressed mRNAs at each THz exposure. Alexandrov BS, Gelev V, Bishop AR, Usheva A, Rasmussen KO. 1) Temperature. Alexandrov et al. Nucl Technol. It was revealed that broadband coherent terahertz waves at 0.5 THz with an average power of 1.2mW produced no obvious influence on cell attachment, morphology, proliferation or differentiation in either human epithelial cells or embryonic stem cells. -, Zaytsev K., et al. Saccharides contain a large number of hydrogen atoms and oxygen atoms, and numerous hydrogen bonds can be formed by themselves or with other biomolecules. Fu WL, Huang Q. Exposure Effects of Terahertz Waves on Primary Neurons and Neuron-like Cells Under Nonthermal Conditions. A friend shaman worked on him..and he came back with TLC too..In January 2022..he was charged by a wild boarhis jugular was open jutting out blood, open wound from neck to rib cage..he managed to walk about 1km back to the car, then lay..said I cant. Zhou J, Liu SG. [56] exposed human peripheral blood leukocytes to 0.12 THz and 0.13 THz terahertz waves for 20min, and no detectable DNA damage was observed. Repair body cells. Moreover, Bock et al. Bookshelf I was so tired I was in bed 98% of my day. Therefore, non-labelled detection could be used to detect DNA molecules by acquiring the absorptive and refractive indices [4]. All genetic information is stored in DNA by the order of paired bases. However, to our knowledge, there are still no publications on the application of terahertz spectroscopy for RNA detection. Effects of Terahertz radiation on the nervous system Effects of Terahertz waves on patients and animal models of neurological diseases Nervous system is more 2003.http://www.cnki.com.cn/Article/CJFDTOTAL-SCEL200304023.htm. Summary. Get the details about iTeracare Magic Wand here. Moreover, terahertz could not alter the conformation of adsorbed proteins, which might be attributed to the adaptive capacity to terahertz wave exposure [46]. Hintzsche et al. Mod Appl Phys. The theoretical model suggested that terahertz wave radiation did not cause rupture or reconstruction of chemical covalent bonds. Antianginal, hypotensive, and hypocoagulative action of terahertz therapy is exposed. It has been demonstrated that water vapor in the air and the solution of biological macromolecules always cause loud noises, resulting in poor sensitivity and weak terahertz spectrum signals. The benefits and features of the Terahertz stone are endless. 6) Broadband. Hellohere is one of our testimonies..of James (dog) and I..I rescued James in 2018. Chen T, Cai ZH, Hu FR, Yin XH, Xu CP. Polysaccharides, carbohydrates with complex molecular structures, are formed by condensation and dehydration of many monosaccharide molecules. 2) Resonance absorption peaks. [Experimental investigation of the safety of terahertz radiation in corneal hydration assessment]. J Grad Sch Chin Acad Sci. But I knew something else was off. Side effects tend to start a week or 2 after the radiotherapy begins. Terahertz is a health power stone that has been gaining attention in recent years. It can penetrate many materials (i.e. Berns MW, Bewley W, Sun CH, Templin P. Free electron laser irradiation at 200 microns affects DNA synthesis in living cells. Therefore, terahertz waves have been widely applied to explore features of the terahertz spectrum of biomacromolecules. Qin Y, Zhang C, Zhu D, Zhu Y, Guo H, You G, Tang S. Opt Express. For example, exposure to terahertz waves for 9h could significantly alter gene expression in MSCs, including increased expression of the transcription factors peroxisome proliferator-activated receptor , adiponectin, glucose transporter 4 and human adipocyte-type fatty acid binding protein 4 and decreased expression of the nuclear receptor transcription factor liver-X-receptor (LXR).
https://doi.org/10.1002/bem.21736. Skinny as death. Interpretation of the space conformation of macromolecules by terahertz spectroscopy will be beneficial for clarifying the molecular mechanisms. Bogomazova et al. https://doi.org/10.3969/j.issn.1002-1175.2005.01.014. Whats the use of spending so much money and effort I hear you say when nothing works. On the right side lies the infrared spectrum. Red light therapy uses the therapeutic application of light energy primarily to aid in the healing of skin and muscular conditions, such as scarring and tendonitis. His biggest scar ,that was a cluster of 1inch skin deep easy ,has DISAPPEARED! Something happens in our cells that makes the outer layer hard. Therefore, further investigations should be conducted in the future.
For example, squamous cell carcinoma-associated genes, such as calcitonin, recombinant human small proline-rich protein-1B, and recombinant human involucrin protein, decreased obviously after radiation. We call it stress. https://doi.org/10.3969/j.issn.1673-7202.2020.11.006. (b)Decrease in the amplitude of a resonant THz-wave absorption peak during the demethylation process. In this paper, we reviewed progress in terahertz technology and the applications and the effects of terahertz waves on biomacromolecules. Summary. Therefore, the development of terahertz technologies has attracted increasing attention in biomedical fields. Take medications as prescribed. The stone is said to bring new ideas and st Sci Rep. 2015;5(1):7749. https://doi.org/10.1038/srep07749. [41] showed that after continuous terahertz radiation at (0.120.18) THz with an average power density of 3.2mW/cm2 for 5min, the space conformation of membrane proteins was changed, several apoptotic proteins were released from mitochondria to cytoplasm, and proteolytic enzymes were also released from lysosomes in the glial cell line C6. Chongqing: The Third Mil Med Univ; 2016. Consistent with that on proteins, the effects of terahertz waves on DNA and RNA were determined by radiation sources, radiation frequency, intensity and duration. Research on terahertz detection of vascular plaques. Spectrosc Spect Anal. The quality of life is less then those with MS or Parkinsons. No torture diets, no yucky shakes, no expensive doctor therapys, just you and the iTeraCare device can make it happen! Dr. Kazukos Onnetsu Therapy, Far Infra-Red and Terahertz and Heat: Together with Dr. Kazukos unique technique, this is a method of treatment to increase the natural healing power and is effective for all illness. He did a 15-20 min treatment. Accessibility WebResults: The reviewed results demonstrate the possibilities of THz spectroscopy and imaging, both pulsed and continuous, for diagnosis of skin melanoma and non-melanoma cancer, dysplasia, scars, and diabetic condition, mainly based on the analysis of 4) Coherence. Therefore, the effects of terahertz waves on organisms might be mediated by biological macromolecules. Biomed Opt Express. Researchers have applied terahertz spectroscopy to analyze the structural characteristics of biological macromolecules. Article Hed bark his fear at any noise..he s still(after 5 yrs) reactive to high pitched soundsand can hear for miles..I had rescued before him a wee dachshund female..shed been chained up for 2yrs alone in a barnfull of ticks and fleas and her own shit..SHE was fearless, joyfull,full of life and just wanted to explore further than her schnozz..the most beautiful gentle soul..she, Cajou, taught her big brother James a lot. Li YC. CAS Tan et al. 5) Perspective. This creates the distinctive red or purple bruises, known as sha.
He MX, Chen T. Application of terahertz science and technology in biomedicine. WebSide effects in adults [ edit] Common adverse drug reactions ( 1% of people) associated with use of the penicillins include diarrhea, hypersensitivity, nausea, rash, neurotoxicity, urticaria (hives), and superinfection (including candidiasis ). Terahertz radiation and the skin: a review. Information and translations of terahertz in the most comprehensive I started feeling funny, ended up being diagnosed with diabetes. (a), (b)Time-dependent electric field of the THz pulse. Biomed Environ Sci. When its new and full, the torchlight is bright and clear, as we use it, the more we use it, the quicker the light diminishes. THz biophotonics; THz dosimetry; THz exposures of biological molecules, cells, and tissues; THz medical diagnosis and therapy; THz technology; THz-wavetissue interactions; thermal and nonthermal effects of THz waves. My brain hurt from tremors and my eyes where closed all the time.I then started having seizures. Cajou found him and coaxed him back up..his skull was open, his spine shocked..he spent 2 months walking in circles..I thought we had a handicapped dog now..with a lot of TLC, he pulled through and was running again. However, no complete spectral analysis of biomacromolecules has been established. 2011;1006(1):7782. Terahertz stone is believed to have the power to resonate with the frequency of your mind and body.
Biomolecular identification and interaction based on terahertz time-domain spectroscopy. Zhao et al. The THz range of the electromagnetic spectrum. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. Similar results were reported by Wilmink et al. Therefore, it is valuable to clarify their relationship, which might result in a major breakthrough in biomedicine. Spectrosc Spect Anal. WebIt can clear blocked passages/ blood vessels and stimulate body detoxification. Other times I would know I was on a flat surface but would look like I was climbing stairs. Phys Med Biol. Application of terahertz spectroscopy in the study of biomacromolecules. The UV beam at 270nm was isolated from the broadband light generated by a xenon-UV-enhanced arc lamp to excite a sample. Mechanistic studies provide strong support for exploring the roles of biomacromolecules in organisms. Therefore, terahertz waves have the potential to be developed as a much more effective tool for analyzing the composition, structure and function of biomacromolecules. Courtesy of the authors. Terahertz pulses can generate a strong electric field without touching or damaging cells, says Hirori. https://doi.org/10.21037/qims.2017.06.02. Several strategies have been tested to improve the spatial resolution, such as insertion of small holes. Sun JH. Mutat Res Genet Toxicol Environ Mutagen.
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